SCHEMBL7120586

SCHEMBL7120586

COc1cc(S(=O)(=O)OS(c2ccc(C(C)(C)C)cc2)(c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)ccc1OS(=O)(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.51
HSD17B3 P37058 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 10/20 0.44
MAPT P10636 8/20 0.44
HTT P42858 5/20 0.44
GAA P10253 4/20 0.44
EYA2 O00167 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
PKM P14618 2/20 0.43
LMNA P02545 5/20 0.43
PTPN1 P18031 1/20 0.41
HPGD P15428 2/20 0.41
POLB P06746 2/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7113151 0.96 ALDH1A1 (0.50) HSD11B1HSD17B3SMN1; SMN2NPC1RAB9A
SCHEMBL7119956 0.91 GFER (0.50) HSD11B1HSD17B3SMN1; SMN2ALDH1A1MAPT
SCHEMBL7112625 0.86 ALDH1A1 (0.56) SMN1; SMN2NPC1RAB9AALDH1A1MAPT
SCHEMBL451539 0.83 HSD11B1 (0.53) HSD11B1HSD17B3NPC1RAB9AALDH1A1
SCHEMBL2634260 0.83 HSD11B1 (0.53) HSD11B1HSD17B3NPC1RAB9AALDH1A1
SCHEMBL7114738 0.83 SMN1; SMN2 (0.49) SMN1; SMN2NPC1RAB9AALDH1A1MAPT
SCHEMBL7112621 0.82 ALDH1A1 (0.48) SMN1; SMN2NPC1RAB9AALDH1A1MAPT
SCHEMBL7120580 0.81 HSD11B1 (0.49) HSD11B1HSD17B3SMN1; SMN2NPC1RAB9A
SCHEMBL7118520 0.81 GFER (0.57) SMN1; SMN2NPC1RAB9AALDH1A1MAPT
SCHEMBL6744474 0.80 TDP1 (0.51) HSD11B1HSD17B3SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6551758-B2 For use in microfabrication of integrated circuits SHIN-ETSU CHEMICAL CO. LTD. (JP) 2003-04-22 US disclosed
US-20020077493-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077493-A1 Novel onium salts, photoacid generators, resist compositions, and patterning process ABL1, PI4K2B, FES HSD11B1 3053/4885HSD17B3 3532/4885SMN1; SMN2 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.