Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.61 |
| ▸ | PLG | P00747 | 2/20 | 0.60 |
| ▸ | KLK1 | P06870 | 2/20 | 0.60 |
| ▸ | PROC | P04070 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114688 | 0.91 | F10 (0.60) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7601136 | 0.90 | F10 (0.58) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7116332 | 0.89 | F10 (0.59) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7598438 | 0.89 | F10 (0.59) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7115851 | 0.88 | F10 (0.77) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7012371 | 0.82 | F10 (0.51) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL6298709 | 0.82 | F10 (0.67) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7006031 | 0.81 | F10 (0.52) | F10PRSS1PLGKLK1PROC | |
| SCHEMBL7119942 | 0.79 | F10 (0.75) | F10PRSS1PLGPROC | |
| SCHEMBL7600812 | 0.79 | F10 (0.72) | F10PRSS1PLGPROCPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| EP-1257530-A1 | AMINOSULFONYLBIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2001062717-A1 | AMINOSULFONYLBIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-08-30 | — | — | WO | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | F10 60/4885PRSS1 34/4885PLG 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.