SCHEMBL7120764

SCHEMBL7120764

Cc1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.76
MAPT P10636 6/20 0.76
PPARG P37231 5/20 0.76
SMN1; SMN2 Q16637 5/20 0.76
MEN1 O00255 4/20 0.76
RORC P51449 4/20 0.76
CYP3A4 P08684 2/20 0.76
MAPK1 P28482 2/20 0.76
LMNA P02545 1/20 0.76
TP53 P04637 1/20 0.76
CYP1A2 P05177 1/20 0.76
CYP2D6 P10635 1/20 0.76
CYP2C9 P11712 1/20 0.76
PKM P14618 1/20 0.76
TSHR P16473 1/20 0.76
NFKB1 P19838 1/20 0.76
CYP2C19 P33261 1/20 0.76
THPO P40225 1/20 0.76
MTOR P42345 1/20 0.76
PMP22 Q01453 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7119682 0.95 KMT2A (0.69) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7130609 0.92 RORC (0.84) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7120562 0.90 KMT2A (0.82) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7118614 0.90 KMT2A (0.62) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7132305 0.90 KMT2A (0.62) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7121705 0.89 RORC (0.80) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL18147432 0.89 RORC (0.80) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7125281 0.88 KMT2A (0.78) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL27589534 0.88 RORC (0.78) KMT2AMAPTPPARGSMN1; SMN2MEN1
SCHEMBL7129479 0.87 KMT2A (0.58) KMT2AMAPTPPARGSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 US disclosed
US-20200196607-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-06-25 US disclosed
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-28 US disclosed
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2019-03-05 US disclosed
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-11-30 US disclosed
US-9781935-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-10 US disclosed
WO-2015187082-A1 NEW PLASMA LIPID LOWERING AGENTS LIPIGON PHARMACEUTICALS AB (SE) 2015-12-10 WO disclosed
US-20030134859-A1 PPAR-gamma modulator SANKYO COMPANY, LIMITED (JP) 2003-07-17 US disclosed
EP-1277729-A1 PPAR (GAMMA) MODULATORS Sankyo Company, Limited (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190090488-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885
US-20030134859-A1 PPAR-gamma modulator PPARG, PPARA, PPARD KMT2A 3291/4885MAPT 4391/4885PPARG 1/4885
US-10219516-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885
US-20200196607-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885
US-20170339961-A1 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD KMT2A 2615/4885MAPT 3431/4885PPARG 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.