SCHEMBL7120865

SCHEMBL7120865

CCCc1cc(C=O)ccc1C

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
ALDH1A3 P47895 6/20 0.40
ALDH3A1 P30838 5/20 0.40
CYP2A6 P11509 1/20 0.40
TAAR1 Q96RJ0 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.36
PTGS2 P35354 1/20 0.36
RAB9A P51151 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FDPS P14324 1/20 0.36
MAPT P10636 1/20 0.35
PTGER4 P35408 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9226581 0.89 ALDH1A3 (0.38) ALDH1A1ALDH1A3ALDH3A1CYP2A6TAAR1
SCHEMBL7125837 0.86 CYP2A6 (0.44) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL16501313 0.85 ALDH1A1 (0.42) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL7117400 0.84 ALDH1A1 (0.42) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL14477876 0.82 ALDH1A1 (0.41) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL20183933 0.81 ALDH1A3 (0.42) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL24071971 0.81 TP53 (0.39) ALDH1A1TAAR1TDP1MAPT
SCHEMBL4765870 0.79 ALDH1A1 (0.50) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR
SCHEMBL3429484 0.79 KDM4E (0.53) ALDH1A1ALDH1A3ALDH3A1KDM4EPTGS2
SCHEMBL23469116 0.79 ALDH1A1 (0.39) ALDH1A1ALDH1A3ALDH3A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945452-B1 SUGAR COMPOUNDS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, PROCESSES FOR THE PREPARATION OF THEM, AND GEL COMPOSITIONS NEW JAPAN CHEM CO LTD (JP) 2003-11-19 EP disclosed
US-6187842-B1 REACTING SORBITOL OR XYLITOL WITH BENZALDEHYE IN PRESENCE OF ACID CATALYST NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-02-13 US disclosed
EP-0945452-A1 SUGAR COMPOUNDS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, PROCESSES FOR THE PREPARATION OF THEM, AND GEL COMPOSITIONS NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-09-29 EP disclosed