SCHEMBL3429484

SCHEMBL3429484

CCCc1cc(C=O)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
PTGS2 P35354 1/20 0.53
RAB9A P51151 1/20 0.53
ALDH1A1 P00352 4/20 0.53
ALDH5A1 P51649 3/20 0.49
ABAT P80404 3/20 0.49
TRIM24 O15164 1/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
ALOX5 P09917 1/20 0.46
AOX1 Q06278 1/20 0.44
PRKCI P41743 1/20 0.42
HMGCR P04035 1/20 0.42
IAPP P10997 2/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
BACE1 P56817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3430982 0.89 ALDH1A1 (0.50) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL3432924 0.88 ALDH1A1 (0.49) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL29954180 0.86 PTGS2 (0.59) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL5607630 0.86 PTGS2 (0.59) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL11503809 0.86 TYR (0.50) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL7251582 0.85 KDM4E (0.53) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL1822487 0.85 LCK (0.50) KDM4EPTGS2RAB9AALDH1A1HPGD
SCHEMBL1822489 0.85 LCK (0.50) KDM4EPTGS2RAB9AALDH1A1HPGD
SCHEMBL7117400 0.82 ALDH1A1 (0.42) KDM4EPTGS2RAB9AALDH1A1ALDH5A1
SCHEMBL5372285 0.81 TRPA1 (0.49) PTGS2ALDH1A1ALOX5PRKCIHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111777746-B Halogen-free flame-retardant epoxy resin composition, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-12-11 CN claimed
CN-111793091-A Halogen-free flame-retardant epoxy resin precursor, composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-10-20 CN claimed
CN-111777746-A Halogen-free flame-retardant epoxy resin composition, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-10-16 CN claimed
JP-4587669-B2 2010-11-24 JP claimed
JP-2005509662-A 2005-04-14 JP claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
CN-111777746-B Halogen-free flame-retardant epoxy resin composition, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-12-11 CN disclosed
CN-111793091-A Halogen-free flame-retardant epoxy resin precursor, composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-10-20 CN disclosed
CN-111777746-A Halogen-free flame-retardant epoxy resin composition, molding compound product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-10-16 CN disclosed
CN-1674897-A Phenylalkanoic acid and phenyloxyalkanoic acid derivatives as HPPAR activators SMITHKLINE BEECHAM CORP (US) 2005-09-28 CN disclosed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US disclosed
CN-1029846-C Process for preparing Thiazolidinone derivatives LILLY CO ELI (US) 1995-09-27 CN disclosed
CN-1052668-A The compound of treatment inflammatory bowel disease LILLY CO ELI (US) 1991-07-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 KDM4E 2158/4885PTGS2 484/4885RAB9A 4360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.