SCHEMBL71209

SCHEMBL71209

COC(=O)c1cccc2nc3c(C(=O)OC)cccc3nc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.74
KMT2A Q03164 2/20 0.74
ATM Q13315 2/20 0.74
GAA P10253 1/20 0.74
ALDH1A1 P00352 3/20 0.55
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
PKN1 Q16512 1/20 0.49
PKN2 Q16513 1/20 0.49
CYP1A2 P05177 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CFTR P13569 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.47
RAD52 P43351 1/20 0.46
SMARCA2 P51531 1/20 0.46
TOP2A P11388 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13653391 0.95 KMT2A (0.68) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL3725674 0.93 KMT2A (0.67) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL30149921 0.93 KMT2A (0.67) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL31659336 0.90 KMT2A (0.63) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL24186161 0.90 KDM4E (0.62) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL16862269 0.89 KDM4E (0.62) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL25168918 0.88 KDM4E (0.61) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL3721864 0.87 KDM4E (0.82) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL3722173 0.87 KDM4E (0.60) KDM4EKMT2AATMGAAALDH1A1
SCHEMBL15255336 0.87 KDM4E (0.59) KDM4EKMT2AATMGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228880-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-07-17 US disclosed
US-20170266215-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2017-09-21 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20100124554-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2010-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228880-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO KDM4E 3013/4885KMT2A 3971/4885ATM 1965/4885
US-20100124554-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO KDM4E 3013/4885KMT2A 3971/4885ATM 1965/4885
US-20170266215-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO KDM4E 3013/4885KMT2A 3971/4885ATM 1965/4885
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885KMT2A 1042/4885ATM 3268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.