Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | RARG | P13631 | 4/20 | 0.48 |
| ▸ | RXRA | P19793 | 12/20 | 0.44 |
| ▸ | RXRG | P48443 | 9/20 | 0.44 |
| ▸ | RXRB | P28702 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928808 | 0.84 | RARB (0.52) | RARARARBRARGRXRARXRG | |
| SCHEMBL6870438 | 0.83 | RARA (0.47) | RARARARBRARGRXRARXRG | |
| SCHEMBL7551634 | 0.76 | RARG (0.51) | RARARARBRARGRXRARXRG | |
| SCHEMBL7551637 | 0.76 | RARG (0.51) | RARARARBRARGRXRARXRG | |
| SCHEMBL7023945 | 0.76 | RARB (0.55) | RARARARBRARGRXRARXRG | |
| SCHEMBL7121488 | 0.76 | MEN1 (0.45) | RARARARBRARGRXRARXRG | |
| SCHEMBL24704034 | 0.72 | MEN1 (0.70) | ALDH1A1KMT2AMEN1LMNANR1H4 | |
| SCHEMBL7527305 | 0.72 | MEN1 (0.70) | ALDH1A1KMT2AMEN1LMNANR1H4 | |
| SCHEMBL648889 | 0.72 | MEN1 (0.70) | ALDH1A1KMT2AMEN1LMNANR1H4 | |
| SCHEMBL6926605 | 0.72 | RXRA (0.49) | RARARARBRARGRXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135053-A1 | For use in human or veterinary conditions, that may be dermatological, rheumatic, respiratory, or cardiovascular and may be used in cosmetics | BERNARDON JEAN-MICHEL | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135053-A1 | For use in human or veterinary conditions, that may be dermatological, rheumatic, respiratory, or cardiovascular and may be used in cosmetics | MITF, TYR, PAH | RARA 52/4885RARB 93/4885RARG 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.