SCHEMBL7121433

SCHEMBL7121433

CCC(C)c1c(OC2CCCC2)c2cc(Cl)ccc2[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
PDE9A O76083 2/20 0.38
MAPK10 P53779 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CNR1 P21554 1/20 0.37
PTGS2 P35354 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
ADORA1 P30542 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114050 0.89 PDE9A (0.44) CSF1RLMNAPDE9ACNR1PTGS2
SCHEMBL7114058 0.87 LMNA (0.36) LMNAMEN1MAPTKMT2ACNR1
SCHEMBL7118632 0.82 SIRT1 (0.44) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7118690 0.81 MEN1 (0.40) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7116744 0.81 SIRT1 (0.46) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7124010 0.80 SIRT1 (0.45) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7114914 0.78 SIRT1 (0.46) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7118635 0.76 GRIN2D (0.53) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7552947 0.74 SIRT1 (0.40) CSF1RLMNAMEN1MAPTKMT2A
SCHEMBL7121233 0.74 SIRT1 (0.42) CSF1RLMNAMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030069271-A1 Quinolone compounds for use in treating viral infections SMITHKLINE BEECHAM CORPORATION 2003-04-10 US claimed
US-20030069271-A1 Quinolone compounds for use in treating viral infections SMITHKLINE BEECHAM CORPORATION 2003-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069271-A1 Quinolone compounds for use in treating viral infections IRF3, MAVS, NQO2 CSF1R 1831/4885LMNA 3043/4885MEN1 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.