Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6011673 | 0.99 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5078893 | 0.91 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5078307 | 0.90 | OPRD1 (0.46) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL6011925 | 0.90 | MEN1 (0.42) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5082007 | 0.89 | MAOB (0.45) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5075632 | 0.88 | OPRD1 (0.50) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5075554 | 0.88 | OPRM1 (0.43) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6011691 | 0.88 | KMT2A (0.41) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5077606 | 0.86 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5075746 | 0.86 | USP2 (0.48) | KMT2AMEN1ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |