SCHEMBL7121803

SCHEMBL7121803

C=CCN(C(=O)O)n1cnc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
APAF1 O14727 1/20 0.41
ASAH1 Q13510 1/20 0.40
ALDH1A1 P00352 2/20 0.40
PKM P14618 1/20 0.40
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 3/20 0.39
AGER Q15109 2/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
ALOX15 P16050 1/20 0.39
LMNA P02545 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22121347 0.84 EGLN3 (0.45) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
SCHEMBL9162968 0.82 SMN1; SMN2 (0.48) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
SCHEMBL11444550 0.76 L3MBTL1 (0.51) EGLN3SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL11429900 0.74 ALDH1A1 (0.42) EGLN3SMN1; SMN2APAF1ALDH1A1PKM
SCHEMBL1516437 0.73 SMN1; SMN2 (0.54) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
SCHEMBL11444565 0.73 SMN1; SMN2 (0.41) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
SCHEMBL7048824 0.72 SMN1; SMN2 (0.52) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
SCHEMBL9159925 0.70 APAF1 (0.50) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1
Carbamic Acid SCHEMBL11602220 0.69 EGLN3 (0.56) EGLN3SMN1; SMN2APAF1KDM4ENPC1
SCHEMBL11824279 0.68 NPC1 (0.45) EGLN3SMN1; SMN2APAF1ASAH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360331-B1 Fabric treatment composition UNILEVER NV (NL) 1995-03-22 EP claimed
EP-0360331-A2 Fabric treatment composition UNILEVER N.V. (NL) 1990-03-28 EP claimed
US-4395274-A BENZIMIDAZOLYL-ALKYL-CARBONATES AND A CHLORINATED PHENOLIC COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1983-07-26 US claimed
US-4228065-A Microbiocidal organopolysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed
EP-0834253-B1 Antimicrobial composition SUGANUMA AKIO (JP) 2003-05-07 EP disclosed
EP-0360331-B1 Fabric treatment composition UNILEVER NV (NL) 1995-03-22 EP disclosed
EP-0360331-A3 FABRIC TREATMENT COMPOSITION UNILEVER N.V. (NL) 1991-06-26 EP disclosed
EP-0237731-B1 MICROBICIDAL AGENTS RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1990-04-04 EP disclosed
EP-0360331-A2 Fabric treatment composition UNILEVER N.V. (NL) 1990-03-28 EP disclosed
EP-0360331-A2 Fabric treatment composition UNILEVER N.V. (NL) 1990-03-28 EP disclosed
EP-0237731-A1 Microbicidal agents RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1987-09-23 EP disclosed
US-4599428-A SALT FORMATION, THIOETHERIFICATION CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1986-07-08 US disclosed
US-4473697-A WITH GASEOUS CHLORINE AND A RHODANIDE CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1984-09-25 US disclosed
US-4402980-A FUNGICIDES; WOOD PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1983-09-06 US disclosed
US-4395274-A BENZIMIDAZOLYL-ALKYL-CARBONATES AND A CHLORINATED PHENOLIC COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1983-07-26 US disclosed
EP-0027646-A1 Process for the preparation of benzimidazole derivatives CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1981-04-29 EP disclosed
US-4228065-A Microbiocidal organopolysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1980-10-14 US disclosed
US-4228065-A Microbiocidal organopolysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1980-10-14 US disclosed
EP-0014443-A1 Dilutable alkyl-benzimidazolecarbamate formulation, process for its preparation and its use as biocide RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1980-08-20 EP disclosed