SCHEMBL7121952

SCHEMBL7121952

CCc1ccccc1[PH](=O)O[PH](=O)c1ccccc1CC

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 2/20 0.33
NISCH Q9Y2I1 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.32
PDK2 Q15119 1/20 0.32
NLRP3 Q96P20 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777172 0.85 L3MBTL1 (0.40) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL779740 0.83 MAPT (0.39) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL28552223 0.80 L3MBTL1 (0.37) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL28546355 0.80 GABRA1 (0.33) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL1425117 0.79 GABRA1 (0.42) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL31091099 0.79 GABRA1 (0.42) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL28554162 0.77 L3MBTL1 (0.39) MAPTL3MBTL1NPSR1ALDH1A1SMN1; SMN2
SCHEMBL28541537 0.77 ALDH1A1 (0.36) GABRA1GABRB2MAPTL3MBTL1NPSR1
SCHEMBL28545745 0.76 TSHR (0.40) MAPTL3MBTL1NPSR1ALDH1A1HPGD
SCHEMBL4127185 0.76 GABRA1 (0.34) GABRA1GABRB2MAPTL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534179-B2 Polytriazine product of cyanate ester monomer or prepolymer and a bismaleimide, and a flame inhibitor of a polyepoxide reacted with an organic phosphorus compound INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-03-18 US disclosed
US-20030003305-A1 Halogen free triazines, bismaleimide/epoxy polymers, prepregs made therefrom for circuit boards and resin coated articles, and use INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-01-02 US disclosed
US-5817736-A Epoxy resin mixtures for prepregs and composites based on phosphorus-modified epoxies, dicy and/or aminobenzoic compounds SIEMENS AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed
US-5587243-A ALSO CONTAINING AROMATIC POLYAMINE HARDENER; FOR PREPREGS AND COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1996-12-24 US disclosed