SCHEMBL7121963

SCHEMBL7121963

CCCCc1ccccc1OC(N)=S

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
LMNA P02545 2/20 0.41
LIPG Q9Y5X9 1/20 0.41
PPARA Q07869 2/20 0.40
PPARG P37231 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
MEN1 O00255 1/20 0.39
NR1I2 O75469 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
MAPT P10636 1/20 0.39
OPRK1 P41145 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338327 1.00 THRA (0.51) THRATHRBALOX5PTGS2LMNA
Hydrogen Sulfide SCHEMBL10740521 0.98 THRA (0.50) THRATHRBALOX5PTGS2LMNA
SCHEMBL4397092 0.97 THRA (0.49) THRATHRBALOX5PTGS2LMNA
SCHEMBL2127453 0.95 THRA (0.48) THRATHRBALOX5PTGS2LMNA
SCHEMBL15174104 0.95 THRA (0.57) THRATHRBALOX5PTGS2LMNA
SCHEMBL28413252 0.94 THRA (0.59) THRATHRBALOX5PTGS2LMNA
SCHEMBL28418186 0.94 THRA (0.59) THRATHRBALOX5PTGS2LMNA
SCHEMBL28416774 0.94 THRA (0.59) THRATHRBALOX5PTGS2LMNA
SCHEMBL28416770 0.94 THRA (0.59) THRATHRBALOX5PTGS2LMNA
SCHEMBL28415892 0.94 THRA (0.59) THRATHRBALOX5PTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111320562-B Method for producing isothiocyanate 旭化成株式会社 2022-08-16 CN disclosed
CN-113880741-A Method for producing isothiocyanate 旭化成株式会社 2022-01-04 CN disclosed
CN-111320562-A Method for producing isothiocyanate 旭化成株式会社 2020-06-23 CN disclosed
EP-0639578-B1 Molybdenum-containing friction-reducing additives SHELL INT RESEARCH (NL) 2003-11-19 EP disclosed
US-5468891-A Molybdenum-containing friction-reducing additives SHELL OIL COMPANY (US) 1995-11-21 US disclosed
EP-0639578-A2 Molybdenum-containing friction-reducing additives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-02-22 EP disclosed