SCHEMBL4397092

SCHEMBL4397092

CCCCc1ccccc1OC(N)=S.NC(O)=S

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
PPARA Q07869 2/20 0.42
PPARG P37231 1/20 0.42
LMNA P02545 2/20 0.40
LIPG Q9Y5X9 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP3A4 P08684 2/20 0.37
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
KDM4E B2RXH2 1/20 0.37
RECQL P46063 1/20 0.37
NR1I2 O75469 1/20 0.37
CHRM2 P08172 1/20 0.37
ADRA2A P08913 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127453 0.98 THRA (0.48) THRATHRBALOX5PTGS2PPARA
SCHEMBL9338327 0.97 THRA (0.51) THRATHRBALOX5PTGS2PPARA
SCHEMBL7121963 0.97 THRA (0.51) THRATHRBALOX5PTGS2PPARA
Hydrogen Sulfide SCHEMBL10740521 0.95 THRA (0.50) THRATHRBALOX5PTGS2PPARA
SCHEMBL9650772 0.94 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL4407225 0.94 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL1606187 0.93 THRA (0.56) THRATHRBALOX5PTGS2PPARA
SCHEMBL15174104 0.92 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL28416770 0.91 THRA (0.59) THRATHRBALOX5PTGS2PPARA
SCHEMBL28416774 0.91 THRA (0.59) THRATHRBALOX5PTGS2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157494-A Phosphorus-free oil-soluble molybdenum complexes as high temperature scale inhibitors 埃科莱布美国股份有限公司 2023-05-23 CN disclosed
CN-116057155-A Phosphorus-free oil-soluble molybdenum complex for high-temperature naphthenic acid corrosion inhibition 埃科莱布美国股份有限公司 2023-05-02 CN disclosed
CN-105255562-B Lubricant oil composite 吉坤日矿日石能源株式会社 2018-02-13 CN disclosed
CN-106190503-A Lubricant oil composite 捷客斯能源株式会社 2016-12-07 CN disclosed
CN-106190504-A Lubricant oil composite 捷客斯能源株式会社 2016-12-07 CN disclosed
CN-101978036-B Lubricant composition for internal combustion engine JX NIPPON OIL & ENERGY CORP. (JP) 2016-04-13 CN disclosed
CN-105255562-A LUBRICANT OIL COMPOSITION NIPPON OIL CORP 2016-01-20 CN disclosed
CN-103805319-B Lubricating oil composition and manufacture method thereof JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-01-06 CN disclosed
CN-105018189-A Lubricating oil compound JX NIPPON OIL & ENERGY CORP 2015-11-04 CN disclosed
EP-2653528-A1 LUBRICATING OIL COMPOSITION FOR SLIDING SECTION COMPRISING ALUMINUM MATERIAL, AND LUBRICATING METHOD JX Nippon Oil & Energy Corporation (JP) 2013-10-23 EP disclosed
EP-2066770-A2 LUBRICATING GREASE COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2009-06-10 EP disclosed
EP-2054491-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS Showa Shell Sekiyu Kabushiki Kaisha (JP) 2009-05-06 EP disclosed
WO-2008028955-A2 LUBRICATING GREASE COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-03-13 WO disclosed
WO-2007129775-A1 GREASE COMPOSITION FOR CONSTANT VELOCITY JOINTS SHOWA SHELL SEKIYU K.K. (JP) 2007-11-15 WO disclosed