SCHEMBL2127453

SCHEMBL2127453

CCCCc1ccccc1OC(N)=S.NC(O)=S.[Zn]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
PPARA Q07869 2/20 0.41
PPARG P37231 1/20 0.41
LMNA P02545 2/20 0.39
LIPG Q9Y5X9 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
KDM4E B2RXH2 1/20 0.36
RECQL P46063 1/20 0.36
NR1I2 O75469 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397092 0.98 THRA (0.49) THRATHRBALOX5PTGS2PPARA
SCHEMBL9338327 0.95 THRA (0.51) THRATHRBALOX5PTGS2PPARA
SCHEMBL7121963 0.95 THRA (0.51) THRATHRBALOX5PTGS2PPARA
Hydrogen Sulfide SCHEMBL10740521 0.94 THRA (0.50) THRATHRBALOX5PTGS2PPARA
SCHEMBL9650772 0.93 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL4407225 0.93 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL1606187 0.91 THRA (0.56) THRATHRBALOX5PTGS2PPARA
SCHEMBL15174104 0.91 THRA (0.57) THRATHRBALOX5PTGS2PPARA
SCHEMBL28416774 0.89 THRA (0.59) THRATHRBALOX5PTGS2PPARA
SCHEMBL28418186 0.89 THRA (0.59) THRATHRBALOX5PTGS2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122034454-A Double-layer tread rubber for improving wet grip performance after tread wear, preparation method and tire 中策橡胶集团股份有限公司 2026-05-15 CN disclosed
CN-122037327-A Flame-retardant bead-protecting rubber composition, mixing method thereof and tire 中策橡胶集团股份有限公司 2026-05-15 CN disclosed
CN-122037339-A Wet response type tire tread rubber based on reversible function of ionic bonds and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN disclosed
CN-122037338-A Tread rubber composition based on bio-based lignin and mixing method thereof 中策橡胶集团股份有限公司 2026-05-15 CN disclosed
CN-122037329-A Double-network crosslinked carcass rubber composition of cracked carbon black-bio-based liquid rubber and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN disclosed
CN-122011522-A Flame-retardant sidewall rubber composition, mixing method thereof and tire 中策橡胶集团股份有限公司 2026-05-12 CN disclosed
CN-116751415-B Sidewall rubber composition for electric buses, mixing method and tire 中策橡胶集团股份有限公司 2025-06-13 CN disclosed
CN-219762612-U Uncured or partially cured girth and article of footwear 全星有限合伙公司 2023-09-29 CN disclosed
CN-116731617-A Composite structure comprising a bonding layer and method for manufacturing the same 耐克创新有限合伙公司 2023-09-12 CN disclosed
CN-116457193-A Composite textile and articles of footwear formed therefrom 耐克创新有限合伙公司 2023-07-18 CN disclosed
EP-1688275-A1 Pneumatic radial tire SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2006-08-09 EP disclosed
WO-2006016699-A1 VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION, METHOD OF PREPARATION THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER PRODUCTS DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO disclosed
WO-2006016714-A1 SILANE-COUPLING-AGENT-TREATED SILICA, PREPARATION METHOD THEREOF, AND VIBRATION-DAMPING AND VIBRATION-ISOLATING RUBBER COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2006-02-16 WO disclosed
US-6881770-B2 Rubber composition for tire and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2005-04-19 US disclosed
US-20030195289-A1 Vulcanizable rubber compounds and process for their production RHEIN CHEMIE RHEINAU GMBH (DE) 2003-10-16 US disclosed
US-20020037950-A1 Rubber composition for tire and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2002-03-28 US disclosed
EP-1176167-A2 Rubber composition for tyre and pneumatic tyre SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2002-01-30 EP disclosed
CN-1217685-A VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION AND PAINTED ELASTOMER COMPOSITION MITSUI CHEMICALS INC (JP) 1999-05-26 CN disclosed
CN-1216055-A RUBBER COMPOSITIONS FOR TIRES MITSUI CHEMICALS INC (JP) 1999-05-05 CN disclosed
CN-1171097-A Norbornene compound having chain polyene group and unsaturated ethylene copolymer prepared using the same MITSUI PETROCHEMICAL IND (JP) 1998-01-21 CN disclosed