Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | BPTF | Q12830 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 2/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.45 |
| ▸ | TUBB | P07437 | 3/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991541 | 0.88 | TPMT (0.61) | LMNABPTFTPMTALDH1A1POLB | |
| SCHEMBL24106208 | 0.88 | LMNA (0.53) | LMNABPTFTPMTTUBB1TUBB4A | |
| SCHEMBL290542 | 0.86 | LMNA (0.69) | LMNATPMTTUBB1TUBB4ATUBB | |
| SCHEMBL3544388 | 0.85 | TPMT (0.69) | LMNABPTFTPMTHTTTSHR | |
| Hydrochloric Acid SCHEMBL29142671 | 0.84 | LMNA (0.67) | LMNATPMTTUBB1TUBB4ATUBB | |
| SCHEMBL7122998 | 0.84 | BPTF (0.53) | LMNABPTFTPMTTUBB1TUBB4A | |
| SCHEMBL28534372 | 0.84 | TPMT (0.53) | BPTFTPMTTSHRALDH1A1POLB | |
| SCHEMBL5779960 | 0.84 | BPTF (0.74) | BPTFTPMTTUBB1TUBB4ATUBB | |
| SCHEMBL6944075 | 0.83 | LMNA (0.78) | LMNABPTFTPMTHTTTSHR | |
| SCHEMBL22991535 | 0.81 | BPTF (0.46) | BPTFTPMTTUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |