Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,4,5-Trimethoxybenzamide SCHEMBL1326890 | 0.87 | TSHR (0.76) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| 3,4,5-Trimethoxybenzamide SCHEMBL4381076 | 0.85 | TSHR (0.73) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL3544388 | 0.84 | TPMT (0.69) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL7122014 | 0.84 | LMNA (0.58) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL18476765 | 0.82 | BPTF (0.60) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL7122998 | 0.82 | BPTF (0.53) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL28534372 | 0.82 | TPMT (0.53) | BPTFTSHRALDH1A1SMN1; SMN2TPMT | |
| SCHEMBL2651012 | 0.81 | ALDH1A1 (0.57) | BPTFHTTALDH1A1SMN1; SMN2TPMT | |
| SCHEMBL16774648 | 0.81 | BPTF (0.71) | BPTFTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL30311442 | 0.80 | TPMT (0.71) | BPTFTSHRAPOBEC3AHTTAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | BPTF 1566/4885TSHR 1807/4885APOBEC3A 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.