SCHEMBL28534372

SCHEMBL28534372

COC(=O)c1cc(I)c(OC)c(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.53
BPTF Q12830 1/20 0.53
CYP3A4 P08684 1/20 0.50
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
TSHR P16473 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
CNR2 P34972 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14024231 0.89 TPMT (0.65) TPMTBPTFCYP3A4KDM4EMAPT
Methyl Syringate SCHEMBL211747 0.87 MEN1 (0.61) TPMTCYP3A4KDM4EMEN1KMT2A
SCHEMBL398872 0.84 BPTF (0.56) TPMTBPTFCYP3A4KDM4EMEN1
SCHEMBL3544388 0.84 TPMT (0.69) TPMTBPTFKDM4EKMT2AMAPT
SCHEMBL7122014 0.84 LMNA (0.58) TPMTBPTFMEN1KMT2AMAPT
SCHEMBL7129669 0.83 BPTF (0.58) BPTFCYP3A4KDM4EMEN1KMT2A
SCHEMBL7122998 0.82 BPTF (0.53) TPMTBPTFKDM4EMEN1KMT2A
SCHEMBL5779960 0.82 BPTF (0.74) TPMTBPTFCYP3A4ALDH1A1TSHR
SCHEMBL401621 0.82 LMNA (0.56) TPMTCYP3A4KDM4EKMT2AMAPT
SCHEMBL17655659 0.81 TPMT (0.53) TPMTCYP3A4KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096114-B Method for synthesizing marine natural product smenodiol 威海海洋生物医药产业技术研究院有限公司 2021-02-26 CN claimed
CN-109096114-B Method for synthesizing marine natural product smenodiol 威海海洋生物医药产业技术研究院有限公司 2021-02-26 CN disclosed