Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122455 | 0.97 | GPR3 (0.41) | WDR5NTRK1GPR3HTR2AALDH1A1 | |
| SCHEMBL7119587 | 0.88 | WDR5 (0.39) | WDR5NTRK1GPR3HTR2AALDH1A1 | |
| SCHEMBL7118953 | 0.88 | GPR3 (0.41) | WDR5NTRK1GPR3HTR2AALDH1A1 | |
| SCHEMBL7127994 | 0.79 | NTRK1 (0.37) | WDR5NTRK1GPR3ALDH1A1HSD17B10 | |
| SCHEMBL7119482 | 0.77 | WDR5 (0.35) | WDR5NTRK1GPR3ALDH1A1HSD17B10 | |
| SCHEMBL7194354 | 0.77 | KDM4E (0.44) | HTR2AALDH1A1HPGDMAPTHTT | |
| SCHEMBL7128822 | 0.75 | NTRK1 (0.38) | WDR5NTRK1GPR3ALDH1A1HSD17B10 | |
| SCHEMBL7129142 | 0.75 | NTRK1 (0.38) | WDR5NTRK1GPR3ALDH1A1HSD17B10 | |
| SCHEMBL7123331 | 0.75 | WDR5 (0.34) | WDR5NTRK1GPR3ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7118358 | 0.75 | NTRK1 (0.40) | WDR5NTRK1GPR3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030148877-A1 | Metallocenes and catalysts for olefin-polymerisation | BASELL TECHNOLOGY COMPANY BV (NL) | 2003-08-07 | — | — | US | disclosed |
| EP-0952978-B1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6451724-B1 | BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030148877-A1 | Metallocenes and catalysts for olefin-polymerisation | MT-CO1, CPNE4, MT-CO3 | WDR5 4206/4885NTRK1 3468/4885GPR3 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.