SCHEMBL7122285

SCHEMBL7122285

CCCCC(O)(S)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
GPR84 Q9NQS5 7/20 0.36
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36
HDAC11 Q96DB2 5/20 0.36
TSHR P16473 4/20 0.36
ALDH1A1 P00352 2/20 0.36
TLR2 O60603 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
FABP4 P15090 2/20 0.36
PTPN1 P18031 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
MEN1 O00255 1/20 0.36
ESR1 P03372 1/20 0.36
ALOX15 P16050 1/20 0.36
PDE4A P27815 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459604 0.85
SCHEMBL8072767 0.83 FDPS (0.36) KMT2ATSHRALDH1A1MEN1HSD17B10
SCHEMBL6624472 0.83 FDPS (0.36) KMT2ATSHRALDH1A1MEN1HSD17B10
Ammonia Solution, Strong SCHEMBL28340659 0.83 FDPS (0.36) KMT2ATSHRALDH1A1MEN1HSD17B10
Hydrochloric Acid SCHEMBL8072773 0.81 FDPS (0.34) KMT2ATSHRALDH1A1MEN1
SCHEMBL4555960 0.78 AKR1B1 (0.39) AKR1B1KMT2AMAPTGPR84PPARG
SCHEMBL5165391 0.78 AKR1B1 (0.39) AKR1B1KMT2AMAPTGPR84PPARG
SCHEMBL2474045 0.76 AKR1B1 (0.37) AKR1B1KMT2AMAPTGPR84PPARG
SCHEMBL636456 0.75 AKR1B1 (0.40) AKR1B1KMT2AGPR84PPARGPPARD
SCHEMBL605019 0.75 TSHR (0.43) AKR1B1KMT2AGPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309739-A1 PROCESS FOR THE PRODUCTION OF 2-HYDROXY-4-METHYLMERCAPTOBUTYRIC ACID Degussa AG (DE) 2003-05-14 EP disclosed
WO-2002016671-A1 PROCESS FOR THE PRODUCTION OF 2-HYDROXY-4-METHYLMERCAPTOBUTYRIC ACID DEGUSSA AG (DE) 2002-02-28 WO disclosed
US-5777151-A REACTING CARBOXYLIC ACID SALT WITH ORGANIC HALOCOMPOUND USING ONIUM SALT PHASE TRANSFER CATALYST RHONE-POULENC CHIMIE (FR) 1998-07-07 US disclosed