Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066692 | 0.90 | FABP4 (0.60) | FABP4HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7134032 | 0.85 | FABP4 (0.49) | FABP4SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7131026 | 0.84 | SMN1; SMN2 (0.46) | FABP4HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7163821 | 0.84 | SMN1; SMN2 (0.43) | FABP4HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8323387 | 0.82 | FABP4 (0.43) | FABP4HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7130963 | 0.82 | PDE4D (0.48) | FABP4 | |
| SCHEMBL7176265 | 0.80 | CNR1 (0.43) | FABP4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5023352 | 0.77 | MAPT (0.45) | HTTSMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL5017992 | 0.76 | LMNA (0.44) | HTTSMN1; SMN2LMNAALDH1A1ATM | |
| SCHEMBL5546407 | 0.75 | LMNA (0.45) | HTTSMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |