Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130963 | 0.90 | PDE4D (0.48) | FABP4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7134032 | 0.87 | FABP4 (0.49) | FABP4MAPTLMNAMEN1KMT2A | |
| SCHEMBL7131026 | 0.82 | SMN1; SMN2 (0.46) | FABP4MAPTLMNAMEN1KMT2A | |
| SCHEMBL7122377 | 0.82 | FABP4 (0.51) | FABP4MAPTLMNAMEN1KMT2A | |
| SCHEMBL7066692 | 0.81 | FABP4 (0.60) | FABP4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7122581 | 0.75 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7163821 | 0.73 | SMN1; SMN2 (0.43) | FABP4MAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL5016454 | 0.72 | PDE4D (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8263103 | 0.72 | PDE4D (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL84871 | 0.72 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |