Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 9/20 | 0.45 |
| ▸ | CNR1 | P21554 | 9/20 | 0.42 |
| ▸ | CNR2 | P34972 | 8/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176265 | 0.91 | CNR1 (0.43) | FABP4CNR1CNR2 | |
| SCHEMBL7131196 | 0.83 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL7122581 | 0.81 | PDE4B (0.53) | — | |
| SCHEMBL7066692 | 0.80 | FABP4 (0.60) | FABP4FABP3 | |
| SCHEMBL5022760 | 0.76 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL7122377 | 0.70 | FABP4 (0.51) | FABP4FABP3 | |
| SCHEMBL3424668 | 0.69 | MAPT (0.50) | FABP4 | |
| SCHEMBL5022790 | 0.67 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL3567919 | 0.67 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL8327219 | 0.66 | GFER (0.49) | FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |