Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MTOR | P42345 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zebularine SCHEMBL12040244 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL12595413 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL13032 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL11910465 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL2563757 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL1649826 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL19656926 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL21842491 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL21474114 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB | |
| Zebularine SCHEMBL1444853 | 1.00 | CDA (1.00) | CDAMAPTLMNAMTORTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315736-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | claimed |
| WO-2002018404-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | claimed |