Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | OGT | O15294 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LRP6 | O75581 | 2/20 | 0.39 |
| ▸ | DKK1 | O94907 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456609 | 0.72 | NPSR1 (0.64) | POLBTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6647933 | 0.70 | ALDH1A1 (0.60) | POLBOGTNOS1TDP1ALDH1A1 | |
| SCHEMBL17260655 | 0.68 | PDE3B (0.71) | POLBOGTNOS1TDP1ALDH1A1 | |
| SCHEMBL118684 | 0.68 | KDM4E (0.67) | POLBOGTNOS1TDP1ALDH1A1 | |
| SCHEMBL29771053 | 0.68 | KDM4E (0.67) | POLBOGTNOS1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27966713 | 0.67 | KMT2A (0.49) | POLBOGTNOS1TDP1ALDH1A1 | |
| SCHEMBL4576717 | 0.66 | GRIN2D (0.55) | NOS1CREBBPPSMB8 | |
| SCHEMBL14565124 | 0.66 | OGT (0.50) | POLBOGTNOS1TDP1ALDH1A1 | |
| SCHEMBL24897510 | 0.66 | CREBBP (0.58) | POLBALDH1A1CREBBPKDM4EMAPT | |
| SCHEMBL9684816 | 0.66 | ALDH1A1 (0.55) | POLBOGTNOS1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |