Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128763 | 0.92 | PTGS2 (0.42) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7129516 | 0.88 | PTGS2 (0.53) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7122505 | 0.87 | PTGS2 (0.50) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7132244 | 0.84 | MAP2K2 (0.36) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7126502 | 0.84 | PTGS2 (0.49) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7122503 | 0.80 | PTGS2 (0.54) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL1032030 | 0.79 | PTGS2 (0.56) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7132137 | 0.79 | PTGS2 (0.55) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL7131340 | 0.74 | PTGS2 (0.67) | PTGS2ABCB11PTGS1PPARGNR1I3 | |
| SCHEMBL6036157 | 0.73 | USP2 (0.49) | PTGS2ABCB11PTGS1PPARGNR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007505-B1 | CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES | NOVARTIS AG (CH) | 2003-04-16 | — | — | EP | claimed |