Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126502 | 0.92 | PTGS2 (0.49) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7122503 | 0.88 | PTGS2 (0.54) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7122861 | 0.88 | PTGS2 (0.39) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7128763 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7131340 | 0.87 | PTGS2 (0.67) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7132244 | 0.84 | MAP2K2 (0.36) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL1032508 | 0.79 | PTGS2 (0.75) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7122501 | 0.79 | PTGS2 (0.64) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL5975932 | 0.77 | CXCL8 (0.57) | PTGS2PTGS1ABCB11NR1I3PPARG | |
| SCHEMBL7132137 | 0.74 | PTGS2 (0.55) | PTGS2PTGS1ABCB11NR1I3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007505-B1 | CERTAIN 5-ALKYL-2-ARYLAMINOPHENYLACETIC ACIDS AND DERIVATIVES | NOVARTIS AG (CH) | 2003-04-16 | — | — | EP | claimed |