Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046789 | 0.81 | SGMS2 (0.52) | PTGER1L3MBTL1KMT2ALMNARXRA | |
| SCHEMBL5046787 | 0.81 | SGMS2 (0.52) | PTGER1L3MBTL1KMT2ALMNARXRA | |
| SCHEMBL10442994 | 0.81 | SGMS2 (0.52) | PTGER1L3MBTL1KMT2ALMNARXRA | |
| SCHEMBL10337677 | 0.81 | PTGER4 (0.53) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| SCHEMBL1396290 | 0.81 | ALDH1A1 (0.57) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| SCHEMBL16039621 | 0.80 | LMNA (0.57) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL18037169 | 0.79 | ALDH1A1 (0.55) | PTGER4PTGER3PTGER2PTGER1L3MBTL1 | |
| SCHEMBL7770355 | 0.79 | ERCC5 (0.46) | SMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL6265289 | 0.79 | ERCC5 (0.46) | SMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL7770353 | 0.79 | ERCC5 (0.46) | SMN1; SMN2KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| EP-2308825-A1 | Process for the preparation of an intermediate for azoxystrobin | Syngenta Limited (GB) | 2011-04-13 | — | — | EP | disclosed |