Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | GPR27 | Q9NS67 | 6/20 | 0.60 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.60 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.60 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126135 | 0.87 | MEN1 (0.69) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL14267570 | 0.83 | MEN1 (0.73) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL7128109 | 0.83 | MEN1 (0.64) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL7125249 | 0.82 | HTT (0.56) | MEN1KMT2AKDM4ESLC10A2SLC10A1 | |
| SCHEMBL6861391 | 0.82 | MEN1 (0.72) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL7120286 | 0.82 | SLC20A2 (0.74) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL5119195 | 0.81 | MEN1 (0.67) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL5124321 | 0.81 | MEN1 (0.66) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL5125023 | 0.81 | MEN1 (0.69) | MEN1KMT2AKDM4EGPR27SLC10A2 | |
| SCHEMBL20560717 | 0.80 | SLC10A2 (0.70) | MEN1KMT2AKDM4EGPR27SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | claimed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | disclosed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC34A3 | MEN1 3779/4885KMT2A 4033/4885KDM4E 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.