Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227896 | 0.75 | TUBB4A (0.53) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL7119112 | 0.71 | TUBB4A (0.49) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL12963403 | 0.66 | TUBB1 (0.58) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL12933316 | 0.66 | TUBB4A (0.54) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL2759516 | 0.66 | PTGS2 (0.54) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL12932837 | 0.65 | PTGS2 (0.44) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL3636265 | 0.65 | DHFR (0.43) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL27871982 | 0.65 | PTGS2 (0.52) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL12963511 | 0.63 | TUBB4A (0.47) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL12963092 | 0.63 | PTGS2 (0.50) | MEN1ALDH1A1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035615-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |