Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127512 | 0.92 | TP53 (0.39) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011709 | 0.92 | CYP3A4 (0.43) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011624 | 0.90 | CACNA1G (0.42) | CACNA2D1CACNB1CACNA1BCACNA1CMAPT | |
| SCHEMBL6011378 | 0.89 | SMN1; SMN2 (0.42) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011475 | 0.89 | LMNA (0.44) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011563 | 0.89 | HRH3 (0.42) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011760 | 0.88 | KMT2A (0.42) | LMNACACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL6011681 | 0.88 | SMN1; SMN2 (0.43) | TP53LMNANPSR1MAPK1CACNA2D1 | |
| SCHEMBL6011783 | 0.87 | HTT (0.44) | TP53NPSR1MAPTHTTMEN1 | |
| SCHEMBL6011554 | 0.87 | MAPT (0.43) | LMNANPSR1TSHRMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | claimed |