Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123726 | 0.92 | TP53 (0.42) | TP53LMNAMAPTGAAGPX4 | |
| SCHEMBL6011709 | 0.91 | CYP3A4 (0.43) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011624 | 0.89 | CACNA1G (0.42) | MAPTGPX4HTR1AHTR7CACNA2D1 | |
| SCHEMBL6011475 | 0.89 | LMNA (0.44) | TP53LMNAMAPTGAANPSR1 | |
| SCHEMBL6011378 | 0.89 | SMN1; SMN2 (0.42) | TP53LMNAMAPTGAAGPX4 | |
| SCHEMBL6011563 | 0.89 | HRH3 (0.42) | TP53LMNANPSR1TSHRMAPK1 | |
| SCHEMBL6011681 | 0.87 | SMN1; SMN2 (0.43) | TP53LMNAMAPTGAAGPX4 | |
| SCHEMBL6011760 | 0.87 | KMT2A (0.42) | LMNAGPX4HTR1AHTR7CACNA2D1 | |
| SCHEMBL6011783 | 0.86 | HTT (0.44) | TP53MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL6011554 | 0.86 | MAPT (0.43) | LMNAMAPTGAANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | claimed |