Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683089 | 0.82 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL3141747 | 0.81 | KDR (0.47) | RAB9AMAPTGAANAMPTALDH1A1 | |
| SCHEMBL447100 | 0.79 | ALDH1A1 (0.44) | NAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL13167592 | 0.78 | NAMPT (0.82) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL14395102 | 0.77 | HTR1F (0.69) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL5626692 | 0.76 | PTGS1 (0.55) | RAB9ANPC1SMN1; SMN2NAMPTMEN1 | |
| SCHEMBL28694761 | 0.75 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL10260121 | 0.74 | TSHR (0.64) | SMN1; SMN2ALDH1A1KCNK3MEN1TSHR | |
| SCHEMBL4498324 | 0.74 | KCNK3 (0.54) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL447011 | 0.74 | KDR (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AADAC, NAT1, PIGO | RAB9A 3627/4885NPC1 650/4885SMN1; SMN2 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.