Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955552 | 0.91 | ALDH1A1 (0.62) | SMN1; SMN2RAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL30365687 | 0.91 | ALDH1A1 (0.62) | SMN1; SMN2RAB9AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28702811 | 0.86 | RAB9A (0.65) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL10224770 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL357738 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL14082548 | 0.82 | DYRK1A (0.63) | SMN1; SMN2RAB9ANPC1ROCK2ATR | |
| SCHEMBL7123963 | 0.82 | RAB9A (0.57) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL12879808 | 0.79 | L3MBTL1 (0.61) | NAMPTATRL3MBTL1MEN1KMT2A | |
| SCHEMBL22236209 | 0.79 | DYRK1A (0.52) | SMN1; SMN2RAB9AMAPTNPC1GAA | |
| SCHEMBL1116630 | 0.78 | ALDH1A1 (0.78) | SMN1; SMN2RAB9AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368083-B | Heteroaryl compounds and their use as therapeutic agents | 东亚首希控股股份有限公司 | 2022-02-01 | — | — | CN | disclosed |