Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656231 | 0.80 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1TDP1 | |
| Benzene SCHEMBL27888124 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL28281698 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL2045248 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL1075415 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL9540908 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL7360791 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL15873589 | 0.76 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1TDP1 | |
| SCHEMBL6585722 | 0.74 | GAA (0.56) | CA1CA2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL10698477 | 0.74 | HTR6 (0.48) | HTR6CA1CA2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634456-A | 5-nitroimino-4H-1, 2, 4-triazole compound and preparation method and application thereof | 赣南师范大学 | 2022-06-17 | — | — | CN | claimed |
| EP-0337229-A2 | Substituted pyri(mi)dines | BAYER AG (DE) | 1989-10-18 | — | — | EP | claimed |
| CN-114634456-B | 5-nitroimino-4H-1, 2, 4-triazole compound and preparation method and application thereof | 赣南师范大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114634456-A | 5-nitroimino-4H-1, 2, 4-triazole compound and preparation method and application thereof | 赣南师范大学 | 2022-06-17 | — | — | CN | disclosed |
| EP-2776411-A1 | MODULATORS OF C3A RECEPTORS | The University of Queensland (AU) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013067578-A1 | MODULATORS OF C3A RECEPTORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-05-16 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | HTR6 1874/4885CA1 2629/4885CA2 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.