Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27888124 | 1.00 | HTR6 (0.50) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27543858 | 0.97 | HTR6 (0.48) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| Iodobenzene SCHEMBL28794484 | 0.89 | HTR6 (0.41) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| Chlorobenzene SCHEMBL27834015 | 0.89 | TSHR (0.46) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL10656231 | 0.78 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL7124034 | 0.76 | HTR6 (0.52) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL14018160 | 0.75 | MMP2 (0.45) | CA1CA2ALDH1A1CA12CA9 | |
| SCHEMBL118977 | 0.75 | GAA (0.54) | CA1CA2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL12017078 | 0.75 | CA2 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL9273311 | 0.75 | ALDH1A1 (0.54) | CA1CA2ALDH1A1HSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903192-A | Preparation method of 3-methoxy isoquinoline compound intermediate | 上海相辉医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-20230242494-A1 | MALONITRILE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-08-03 | — | — | US | claimed |
| EP-4153577-A1 | NEW MALONITRILE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-03-29 | — | — | EP | claimed |
| CN-115551837-A | Novel malononitrile derivatives | 豪夫迈·罗氏有限公司 | 2022-12-30 | — | — | CN | claimed |
| US-11326015-B1 | Cyanate ester resin | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2022-05-10 | — | — | US | claimed |
| WO-2021233854-A1 | NEW MALONITRILE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-11-25 | — | — | WO | claimed |
| CN-110234423-A | It is capable of the method for the detonation of material of detonation for avoiding and extinguishing | 拜耳股份公司 | 2019-09-13 | — | — | CN | claimed |
| CN-106279167-A | Matrine compound derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2017-01-04 | — | — | CN | claimed |
| CN-102659783-B | N-substituted sophora flavescens olefine acid derivative as well as preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2015-04-22 | — | — | CN | claimed |
| CN-100406433-C | Process for the cyanation of aldehydes | KING S COLLEGE LONDON (GB) | 2008-07-30 | — | — | CN | claimed |
| EP-1543156-A4 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | UNIV LELAND STANFORD JUNIOR (US) | 2005-12-21 | — | — | EP | claimed |
| EP-1543156-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | The Board of Trustees of the Leland Stanford Junior University (US) | 2005-06-22 | — | — | EP | claimed |
| US-20040259102-A1 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | STANFORD UNIVERSITY (US) | 2004-12-23 | — | — | US | claimed |
| EP-0926136-B1 | Process for producing and method of crystallizing 2-azabicyclo(2.2.1)hept-5-en-3-one | KURARAY CO (JP) | 2004-05-12 | — | — | EP | claimed |
| WO-2004010101-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-01-29 | — | — | WO | claimed |
| EP-1090013-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067255-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-29 | — | — | WO | claimed |
| EP-0926136-A2 | Process for producing and method of crystallizing 2-azabicyclo(2.2.1)hept-5-en-3-one | KURARAY CO., LTD. (JP) | 1999-06-30 | — | — | EP | claimed |
| US-4386935-A | Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | claimed |
| US-4175175-A | POLYSULFONES, POLYSULFONAMIDES | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11326015-B1 | Cyanate ester resin | TH, TYR, LPO | HTR6 617/4885CA1 1316/4885CA2 1697/4885 |
| US-20230242494-A1 | MALONITRILE DERIVATIVES | MAL2, ME1, C5 | HTR6 3678/4885CA1 2583/4885CA2 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.