Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541319 | 0.80 | TLR9 (0.64) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL1344338 | 0.80 | TLR9 (0.80) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL1344341 | 0.80 | TLR9 (0.80) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL2787588 | 0.80 | TLR9 (0.80) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL12970040 | 0.76 | TLR9 (0.58) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| (Ethenylsulfonyl)Benzene SCHEMBL1331367 | 0.76 | TLR9 (0.58) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL10825832 | 0.76 | TLR9 (1.00) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| (Ethenylsulfonyl)Benzene SCHEMBL1332952 | 0.76 | TLR9 (0.58) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| (Ethenylsulfonyl)Benzene SCHEMBL45672 | 0.76 | TLR9 (0.58) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 | |
| SCHEMBL11273158 | 0.76 | TLR9 (0.58) | TLR9HTR6ALDH1A1MCOLN3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947867-A | Bicyclic alkyl compound and synthesis | 卡利拉制药公司 | 2018-12-07 | — | — | CN | claimed |
| CN-114848699-B | Composition with uric acid reducing effect and preparation method and application thereof | 安琪纽特股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114634456-A | 5-nitroimino-4H-1, 2, 4-triazole compound and preparation method and application thereof | 赣南师范大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-106232567-B | Propalane derivatives and synthesis | 里科瑞尔姆IP控股有限责任公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-3822252-A1 | COMPOSITION OF FUSED TRICYCLIC GAMMA-AMINO ACID DERIVATIVE AND PREPARATION THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2021-05-19 | — | — | EP | disclosed |
| CN-108947867-A | Bicyclic alkyl compound and synthesis | 卡利拉制药公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-108658867-A | A kind of synthetic method of the ketone compounds of pyrazoline containing benzenesulfonyl | 青岛农业大学 | 2018-10-16 | — | — | CN | disclosed |
| EP-2776411-A1 | MODULATORS OF C3A RECEPTORS | The University of Queensland (AU) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013067578-A1 | MODULATORS OF C3A RECEPTORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-05-16 | — | — | WO | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-0302792-B1 | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI SA (FR) | 1994-10-26 | — | — | EP | disclosed |
| US-5340820-A | Useful for treatment of ocular diseases, angina pectoris, hypertension and arrhythmia | ELF SANOFI (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0302793-B1 | Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI ELF (FR) | 1993-12-15 | — | — | EP | disclosed |
| US-5215988-A | Treating angina, hypertension, arrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-06-01 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4994474-A | Hypotensive agents | SANOFI (FR) | 1991-02-19 | — | — | US | disclosed |
| EP-0302792-A2 | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302793-A2 | Aralkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | ELF SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0173320-A1 | Substituted carbonylphenylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |