SCHEMBL7541319

SCHEMBL7541319

O=S(=O)([CH]S(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.64
HTR6 P50406 1/20 0.55
ALDH1A1 P00352 4/20 0.54
MCOLN3 Q8TDD5 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1344341 0.82 TLR9 (0.80) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL2787588 0.82 TLR9 (0.80) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL1344338 0.82 TLR9 (0.80) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL7124038 0.80 TLR9 (0.61) TLR9HTR6ALDH1A1MCOLN3CYP1A2
(Ethenylsulfonyl)Benzene SCHEMBL1331367 0.78 TLR9 (0.58) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL10825832 0.78 TLR9 (1.00) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL12970040 0.78 TLR9 (0.58) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL10826201 0.78 TLR9 (1.00) TLR9HTR6ALDH1A1MCOLN3CYP1A2
(Ethenylsulfonyl)Benzene SCHEMBL1332952 0.78 TLR9 (0.58) TLR9HTR6ALDH1A1MCOLN3CYP1A2
SCHEMBL11273158 0.78 TLR9 (0.58) TLR9HTR6ALDH1A1MCOLN3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 EP claimed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US claimed
EP-0417555-A1 Pentamethine dyes and derivatives BAYER AG (DE) 1991-03-20 EP claimed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP claimed
CN-116789578-A Chiral monofluoro bis (arylsulfonyl) methyl/(deuterated) monofluoromethyl substituted chiral allyl compounds and synthesis method thereof 华东师范大学 2023-09-22 CN disclosed
EP-0819981-B1 Radiation sensitive resin composition JSR CORP (JP) 2002-06-05 EP disclosed
US-5952150-A COMPRISING A DISULFONYLMETHANE DERIVATIVE, A RESIN PROTECTED BY AN ACID DECOMPOSABLE GROUP OR AN ALKALI-SOLUBLE RESIN AND AN ALKALI SOLUBILITY CONTROL AGENT; PHOTORESISTS JSR CORPORATION (JP) 1999-09-14 US disclosed
US-5859042-A ALOPECIA, ACNE, DISEASES OF THE PROSTATE GLANDS ONO PHARMACEUTICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0819981-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-01-21 EP disclosed
EP-0433024-B1 Colour recording medium containing leuco dye FUJI PHOTO FILM CO LTD (JP) 1994-09-21 EP disclosed
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 EP disclosed
US-5138070-A Laser transfer printing; opticalrecording media BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
EP-0433024-A1 Colour recording medium containing leuco dye FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
EP-0417555-A1 Pentamethine dyes and derivatives BAYER AG (DE) 1991-03-20 EP disclosed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP disclosed