SCHEMBL11273158

SCHEMBL11273158

N[CH]S(=O)(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.58
CA1 P00915 4/20 0.52
CA2 P00918 4/20 0.52
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ALDH1A1 P00352 2/20 0.50
HTR6 P50406 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10785472 0.80 TLR9 (0.67) TLR9CA1CA2CA12CA9
SCHEMBL10950780 0.80 TLR9 (0.67) TLR9CA1CA2CA12CA9
SCHEMBL1344338 0.78 TLR9 (0.80) TLR9CA1CA2CA12CA9
SCHEMBL1344341 0.78 TLR9 (0.80) TLR9CA1CA2CA12CA9
SCHEMBL7541319 0.78 TLR9 (0.64) TLR9CA1CA2CA12CA9
SCHEMBL2787588 0.78 TLR9 (0.80) TLR9CA1CA2CA12CA9
SCHEMBL7124038 0.76 TLR9 (0.61) TLR9CA1CA2CA12CA9
SCHEMBL27338409 0.75 TLR9 (0.67) TLR9CA1CA2CA12CA9
SCHEMBL8488153 0.75 CA2 (0.56) TLR9CA1CA2CA12CA9
SCHEMBL12970040 0.74 TLR9 (0.58) TLR9CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471338-B Novel azaheterocyclic compounds MERCK PATENT GMBH 2014-07-02 CN claimed
CN-102970867-A Aryl and heteroaryl sulfonamides as active agents against abiotic plant stress BAYER IP GMBH 2013-03-13 CN claimed
CN-102471338-A Novel azaheterocyclic compounds MERCK PATENT GMBH 2012-05-23 CN claimed
WO-2023067170-A1 COMPOUNDS FOR THE TREATMENT OF MALARIA FUNDACIÓ INSTITUT DE BIOENGINYERIA DE CATALUNYA (ES) 2023-04-27 WO disclosed
CN-107849024-A With as indoleamine 2, the benzimidazole and imidazopyridine imido of 3 dioxygenase inhibitor activities are for benzamide compound 吉利德科学公司 2018-03-27 CN disclosed
CN-102471338-B Novel azaheterocyclic compounds MERCK PATENT GMBH 2014-07-02 CN disclosed
CN-102970867-A Aryl and heteroaryl sulfonamides as active agents against abiotic plant stress BAYER IP GMBH 2013-03-13 CN disclosed
CN-102471338-A Novel azaheterocyclic compounds MERCK PATENT GMBH 2012-05-23 CN disclosed
CN-1902191-A Amidopyrazole derivative DAIICHI SEIYAKU CO (JP) 2007-01-24 CN disclosed
EP-0055099-A1 Penicillin derivatives ICI PHARMA (FR) 1982-06-30 EP disclosed