SCHEMBL7124208

SCHEMBL7124208

Cc1ccccc1C(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
HTT P42858 2/20 0.63
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
ALDH1A1 P00352 1/20 0.58
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10722342 0.84 KMT2A (0.68) LMNAKMT2AMEN1KDM4EALDH1A1
SCHEMBL755164 0.83 HTT (0.60) LMNAHTTKMT2AMEN1KDM4E
SCHEMBL10722320 0.83 HTT (0.89) HTTKMT2AMEN1ALDH1A1
SCHEMBL10726980 0.80 LMNA (0.81) LMNAKMT2AMEN1GAAALDH1A1
SCHEMBL31538996 0.80 KMT2A (0.77) LMNAHTTKMT2AMEN1KDM4E
SCHEMBL29352141 0.80 LMNA (1.00) LMNAKMT2AMEN1GAAALDH1A1
SCHEMBL3088384 0.80 HTT (0.77) HTTKMT2AMEN1ALDH1A1
SCHEMBL12261981 0.79 LMNA (0.54) LMNAHTTKMT2AMEN1KDM4E
SCHEMBL14590548 0.79 ALDH1A1 (0.67) LMNAKMT2AMEN1GAAALDH1A1
SCHEMBL6744239 0.78 ALDH1A1 (0.71) LMNAKMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed