Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.57 |
| ▸ | ALB | P02768 | 3/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470705 | 0.78 | MAPT (0.41) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL8469517 | 0.78 | MAPT (0.41) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL6403793 | 0.77 | LMNA (0.52) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL8910840 | 0.77 | LMNA (0.52) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL1628462 | 0.77 | LMNA (0.52) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL21239415 | 0.77 | LMNA (0.52) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL9067540 | 0.77 | ALB (0.59) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL9067244 | 0.77 | ALB (0.59) | LMNAPDE3AALBCACNA1FMAPT | |
| SCHEMBL7124283 | 0.77 | ALB (0.59) | LMNAPDE3AALBCACNA1FMAPT | |
| 4'-Thio-2'-Deoxycytidine SCHEMBL24043143 | 0.76 | LMNA (0.53) | LMNAPDE3AALBCACNA1FMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560794-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. | IAF BIOCHEM INT (CA) | 1993-09-22 | — | — | EP | claimed |