Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylbenzene SCHEMBL28769972 | 0.88 | TAAR1 (0.44) | LTA4HACHEMAPK1 | |
| Trifluoromethylbenzene SCHEMBL9651235 | 0.83 | ALDH1A1 (0.52) | LTA4HTSHRALDH1A1MAPK1TP53 | |
| SCHEMBL11133821 | 0.83 | LTA4H (0.44) | LTA4HTSHRALDH1A1MAPK1TP53 | |
| SCHEMBL15559247 | 0.80 | KIF11 (0.47) | LTA4HTSHRALDH1A1MAPK1TP53 | |
| Biphenyl SCHEMBL3197075 | 0.79 | LTA4H (0.52) | LTA4HTSHRALDH1A1MAPK1TP53 | |
| SCHEMBL27812912 | 0.79 | TSHR (0.44) | LTA4HTSHRALDH1A1HPGDMEN1 | |
| SCHEMBL8466133 | 0.79 | LTA4H (0.44) | LTA4HTSHRALDH1A1MAPK1TP53 | |
| SCHEMBL4478143 | 0.79 | KIF11 (0.49) | LTA4HTSHRALDH1A1LMNAMEN1 | |
| Tert-Butylbenzene SCHEMBL27715546 | 0.78 | TSHR (0.46) | LTA4HACHETSHRALDH1A1MAPK1 | |
| Benzene SCHEMBL27778100 | 0.78 | HTT (0.56) | LTA4HTSHRALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027316-B1 | SYNTHESIS OF ARYL ETHERS, METHODS AND REAGENTS RELATED THERETO | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1254884-A2 | Preparation of vinyl ethers from alcohols and alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1245553-A2 | Palladium-catalysed synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-02 | — | — | EP | disclosed |