Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.59 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.59 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 4/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.45 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.45 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128140 | 0.94 | SLC10A6 (0.61) | SLC10A6SLC10A2SLC10A1CCR2GPR27 | |
| SCHEMBL7213174 | 0.81 | SLC10A6 (0.61) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL7208733 | 0.81 | SLC10A6 (0.71) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL5115455 | 0.80 | SLC10A6 (0.88) | SLC10A6SLC10A2SLC10A1CCR2GPR27 | |
| SCHEMBL27575233 | 0.79 | SLC10A6 (0.58) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL7117455 | 0.78 | SLC10A2 (0.60) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL6856038 | 0.78 | MEN1 (0.70) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL7439994 | 0.77 | SLC10A2 (0.55) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL7126120 | 0.76 | SLC10A6 (0.98) | SLC10A6SLC10A2SLC10A1GPR27KMT2A | |
| SCHEMBL6862376 | 0.76 | SLC10A6 (0.76) | SLC10A6SLC10A2SLC10A1GPR27KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | claimed |
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | claimed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | claimed |
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | disclosed |
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | disclosed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC34A3 | SLC10A6 19/4885SLC10A2 57/4885SLC10A1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.