Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.54 |
| ▸ | THRB | P10828 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025061 | 0.91 | THRA (0.60) | THRATHRB | |
| SCHEMBL6658103 | 0.85 | THRA (0.58) | THRATHRB | |
| SCHEMBL7057569 | 0.84 | THRB (0.41) | THRATHRB | |
| SCHEMBL6664392 | 0.83 | THRA (0.60) | THRATHRB | |
| SCHEMBL6658666 | 0.80 | THRA (0.59) | THRATHRB | |
| SCHEMBL6660253 | 0.79 | THRA (0.56) | THRATHRB | |
| SCHEMBL6658101 | 0.79 | THRA (0.58) | THRATHRB | |
| SCHEMBL7057567 | 0.78 | THRB (0.38) | THRATHRB | |
| SCHEMBL8798722 | 0.78 | THRA (0.76) | THRATHRB | |
| SCHEMBL6661578 | 0.77 | THRA (0.58) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |