Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.38 |
| ▸ | THRA | P10827 | 11/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057569 | 0.84 | THRB (0.41) | THRBTHRA | |
| SCHEMBL7025061 | 0.79 | THRA (0.60) | THRBTHRA | |
| SCHEMBL7124400 | 0.78 | THRA (0.54) | THRBTHRA | |
| SCHEMBL7053473 | 0.72 | THRA (0.33) | THRBTHRA | |
| SCHEMBL3635237 | 0.64 | TSHR (0.54) | THRB | |
| SCHEMBL10777860 | 0.63 | THRA (0.53) | THRBTHRA | |
| SCHEMBL13044480 | 0.63 | THRA (0.49) | THRBTHRA | |
| SCHEMBL8800887 | 0.62 | THRA (0.62) | THRBTHRA | |
| SCHEMBL8799562 | 0.61 | THRA (0.69) | THRBTHRA | |
| SCHEMBL23863357 | 0.60 | THRB (0.52) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |