Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124686 | 0.75 | — | — | |
| SCHEMBL7127277 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MAPTELOVL6 | |
| SCHEMBL28481811 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL7125341 | 0.70 | ALDH1A1 (0.33) | ALDH1A1MAPTELOVL6 | |
| SCHEMBL7115709 | 0.70 | KMT2A (0.38) | ALDH1A1MAPT | |
| SCHEMBL24449902 | 0.69 | KMT2A (0.43) | ALDH1A1MAPT | |
| SCHEMBL7130397 | 0.68 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL20232737 | 0.67 | CYP1A2 (0.47) | ALDH1A1 | |
| SCHEMBL9892856 | 0.65 | TP53 (0.38) | ALDH1A1MAPT | |
| SCHEMBL21954013 | 0.65 | L3MBTL1 (0.36) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | ALDH1A1 1333/4885MAPT 4370/4885ELOVL6 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.