Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119235 | 0.86 | CYP2A6 (0.43) | SLC6A2SLC6A4SLC6A3CHRNA7HPGD | |
| SCHEMBL6098344 | 0.85 | CHRNB4 (0.39) | CHRNA7SSTR3SMYD3 | |
| SCHEMBL7121745 | 0.85 | CHRNB2 (0.40) | CHRNA7SSTR3SMYD3 | |
| SCHEMBL6100330 | 0.84 | SSTR3 (0.47) | SSTR3 | |
| SCHEMBL7124945 | 0.84 | CHRNA7 (0.37) | CHRNA7SSTR3TAS1R3TAS1R2SMYD3 | |
| SCHEMBL7121774 | 0.84 | CHRNA7 (0.36) | CHRNA7SSTR3SMYD3 | |
| SCHEMBL7124032 | 0.84 | SSTR3 (0.45) | SLC6A3CHRNA7SSTR3TAS1R3TAS1R2 | |
| SCHEMBL7121130 | 0.84 | SLC6A3 (0.40) | SLC6A2SLC6A4SLC6A3CHRNA7SSTR3 | |
| SCHEMBL7125111 | 0.84 | DRD4 (0.40) | CHRNA7SSTR3SMYD3 | |
| SCHEMBL6102157 | 0.84 | F10 (0.45) | SLC6A4SLC6A3CHRNA7SSTR3TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | claimed |
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | CYP7B1, UGT2B7, CYP1B1 | SLC6A2 1156/4885SLC6A4 2137/4885SLC6A3 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.