SCHEMBL7125348

SCHEMBL7125348

N#Cc1cc2c(c3ccccc13)C1=CC=CCC1=N2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NCOA3 Q9Y6Q9 1/20 0.34
IMPDH2 P12268 1/20 0.31
IMPDH1 P20839 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7212210 0.79 TRPA1 (0.33) TSHR
SCHEMBL272379 0.66 IDO1 (0.31)
SCHEMBL5176273 0.65
SCHEMBL3216631 0.59 ESR2 (0.42) TSHR
SCHEMBL4506363 0.58 GPR3 (0.33)
SCHEMBL7813270 0.57 TSHR (0.46) NCOA3IMPDH2IMPDH1TSHR
SCHEMBL7813266 0.57 NCOA3 (0.44) NCOA3IMPDH2IMPDH1TSHR
SCHEMBL11228244 0.57 IMPDH2 (0.59) NCOA3IMPDH2IMPDH1TSHR
SCHEMBL29489135 0.57 IMPDH2 (0.64) NCOA3IMPDH2IMPDH1TSHR
SCHEMBL29489124 0.57 CA1 (0.54) NCOA3IMPDH2IMPDH1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010008669-A1 Optical information recording medium TAIYO YUDEN CO., LTD., 16-20 UENO 6-CHOME, TAITO-KU, TOKYO, 110-0005 JAPAN 2001-07-19 US claimed
EP-1107243-A2 Optical information recording medium Taiyo Yuden Co., Ltd. (JP) 2001-06-13 EP claimed
EP-1107243-A3 Optical information recording medium Taiyo Yuden Co., Ltd. (JP) 2003-05-28 EP disclosed
US-20010008669-A1 Optical information recording medium TAIYO YUDEN CO., LTD., 16-20 UENO 6-CHOME, TAITO-KU, TOKYO, 110-0005 JAPAN 2001-07-19 US disclosed
US-20010008669-A1 Optical information recording medium TAIYO YUDEN CO., LTD., 16-20 UENO 6-CHOME, TAITO-KU, TOKYO, 110-0005 JAPAN 2001-07-19 US disclosed
EP-1107243-A2 Optical information recording medium Taiyo Yuden Co., Ltd. (JP) 2001-06-13 EP disclosed
EP-1107243-A2 Optical information recording medium Taiyo Yuden Co., Ltd. (JP) 2001-06-13 EP disclosed