Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130653 | 1.00 | MAPT (0.51) | MAPTRAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7132109 | 1.00 | MAPT (0.51) | MAPTRAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL12312081 | 0.95 | MAPT (0.56) | MAPTRAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7133129 | 0.88 | RARB (0.59) | MEN1HTTKMT2ARARBTDP1 | |
| SCHEMBL7132348 | 0.88 | RARB (0.59) | MEN1HTTKMT2ARARBTDP1 | |
| SCHEMBL7133856 | 0.88 | RARB (0.59) | MEN1HTTKMT2ARARBTDP1 | |
| SCHEMBL6024892 | 0.87 | LMNA (0.49) | MAPTKMT2AL3MBTL1GAACYP3A4 | |
| SCHEMBL13882235 | 0.86 | LMNA (0.48) | MAPTRAB9AKMT2AL3MBTL1GAA | |
| SCHEMBL13882220 | 0.86 | NPC1 (0.42) | MAPTMEN1ALDH1A1KMT2ARARB | |
| SCHEMBL1532520 | 0.85 | KCNH2 (0.47) | MAPTALDH1A1HTTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6666989-B1 | Electrical and electro-optic apparatus comprising spaced glass panels having polyethers and electrodes on the interior surfaces, used as detectors, screens and in nonlinear optical apparatus | QINETIQ LIMITED (GB) | 2003-12-23 | — | — | US | disclosed |
| EP-1060226-A1 | LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999043763-A1 | LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-09-02 | — | — | WO | disclosed |