Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133856 | 1.00 | RARB (0.59) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL7132348 | 1.00 | RARB (0.59) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL1532562 | 0.96 | TP53 (0.56) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL8096022 | 0.96 | TP53 (0.56) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL12353208 | 0.95 | TP53 (0.54) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL6025789 | 0.93 | PLA2G4B (0.52) | RARBTP53TSHRPLA2G4BHTT | |
| SCHEMBL7130653 | 0.88 | MAPT (0.51) | RARBHTTMEN1KMT2ATDP1 | |
| SCHEMBL7125555 | 0.88 | MAPT (0.51) | RARBHTTMEN1KMT2ATDP1 | |
| SCHEMBL7132109 | 0.88 | MAPT (0.51) | RARBHTTMEN1KMT2ATDP1 | |
| SCHEMBL6024892 | 0.84 | LMNA (0.49) | TP53TSHRPLA2G4BKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6666989-B1 | Electrical and electro-optic apparatus comprising spaced glass panels having polyethers and electrodes on the interior surfaces, used as detectors, screens and in nonlinear optical apparatus | QINETIQ LIMITED (GB) | 2003-12-23 | — | — | US | disclosed |