Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015370 | 0.88 | KDM4E (0.60) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL9674267 | 0.87 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL1797516 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL6002909 | 0.83 | HPGD (0.69) | ALDH1A1MAPTKDM4EPOLBLMNA | |
| SCHEMBL417874 | 0.83 | RXFP1 (0.54) | ALDH1A1KDM4EHSD17B10LMNARXFP1 | |
| SCHEMBL1794335 | 0.83 | SMN1; SMN2 (0.69) | ALDH1A1MAPTKDM4EPOLBLMNA | |
| SCHEMBL1799240 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL6510154 | 0.82 | KMT2A (0.63) | ALDH1A1KDM4EHSD17B10POLBLMNA | |
| SCHEMBL30556513 | 0.82 | RXFP1 (0.53) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL30044907 | 0.82 | KMT2A (0.63) | ALDH1A1KDM4EHSD17B10POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069271-A1 | Quinolone compounds for use in treating viral infections | SMITHKLINE BEECHAM CORPORATION | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069271-A1 | Quinolone compounds for use in treating viral infections | IRF3, MAVS, NQO2 | ALDH1A1 1742/4885MAPT 2817/4885KDM4E 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.